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- Sulfotransferases: SULT Genes, Phase II Detoxification, and . . .
Sulfotransferases (SULTs) are a family of enzymes that play a critical role in the phase II detoxification process These enzymes take substances that need to be eliminated, such as hormones, toxicants, and neurotransmitters, and attach a sulfur-containing molecule called a sulfonate group (SO 3–)
- Updated perspectives on the cytosolic sulfotransferases . . .
The cytosolic sulfotransferases (SULTs) are Phase II detoxifying enzymes that mediate the sulfate conjugation of numerous xenobiotic molecules While the research on the SULTs has lagged behind the research on Phase I cytochrome P-450 enzymes and
- Sulfotransferase - Wikipedia
In biochemistry, sulfotransferases (SULTs) are transferase enzymes that catalyze the transfer of a sulfo group (R−SO− 3) from a donor molecule to an acceptor alcohol (R−OH) or amine (R−NH2) [1] The most common sulfo group donor is 3'-phosphoadenosine-5'-phosphosulfate (PAPS)
- Sulfotransferases (SULTs) - Toxicology
Sulfotransferases (SULTs) are a family of enzymes that play a crucial role in the metabolism of various endogenous and exogenous compounds These enzymes are predominantly found in the liver but are also present in other tissues
- Structure, dynamics and selectivity in the sulfotransferase . . .
The human cystosolic sulfotransferases (SULTs) comprise a 13-member family of enzymes that catalyze transfer of the sulfuryl-group (–SO 3) from 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to the hydroxyl and primary amine moieties of thousands of endogenous and xenobiotic acceptors
- Pharmacogenetics of human sulfotransferases and impact of . . .
Sulfotransferases (SULTs) are Phase II drug-metabolizing enzymes (DMEs) catalyzing the sulfation of a variety of endogenous compounds, natural products, and drugs
- SULT genetic polymorphisms: physiological, pharmacological . . .
Cytosolic sulfotransferases (SULTs)-mediated sulfation is critically involved in the metabolism of key endogenous compounds such as catecholamines and steroid thyroid hormones, as well as drugs and other xenobiotics
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